妛暥娰堛妛惗棟妛尋媶強

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妛暥娰堛妛惗棟妛尋媶強
尋媶強挿儊僢僙乕僕
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尋媶丒妶摦曬崘
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尋媶椣棟埾堳夛
 

尋媶丒妶摦曬崘

2022/10/24

 

乽椦暃妛挿偲彫帣堛椕僙儞僞乕偼嫟摨偱彫帣敀寣昦偺夝愅傪峴偄丄

梊屻偵娭傢傞堚揱巕曄堎偺堦晹傪柧傜偐偵偟偰榑暥敪昞偟傑偟偨丅乿

 
  1. Kaburagi T, Yamato G, Shiba N, Yoshida K, Hara Y, Tabuchi K, Shiraishi Y, Ohki K, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y. Haematologica. 2022 Mar 1;107(3):583-592. doi: 10.3324/haematol.2020.269431.PMID: 33730843
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  3.                                                                  撪梕徯夘 
  4. 彫帣媫惈崪悜惈敀寣昦(AML)偺栺40%偼嵞敪擄帯偱偁傞丅椦暃妛挿偲孮攏導棫彫帣堛椕僙儞僞乕偼嫟摨偱彫帣AML偺夝愅傪峴偄丄梊屻偵娭傢傞堚揱巕曄堎偺堦晹傪柧傜偐偵偟偰榑暥敪昞偟傑偟偨丅擔杮彫帣敀寣昦儕儞僷庮尋媶僌儖乕僾(JPLSG) AML-05椪彴帋尡偵搊榐偝傟偨328徢椺傪懳徾偵僒儞僈乕僔乕働儞僗朄偲師悽戙僔乕働儞僒乕傪梡偄偰RAS宱楬堎忢偺栐梾揑夝愅傪峴偄丄椪彴憸偲偺娭楢傪専摙偟偨丅摨掕偟偨堎忢偼NF1 (7椺, 2.1%), PTPN11 (15椺丄4.6%), CBL (6椺, 1.8%), NRAS (44椺,13.4%), KRAS (12椺,3.7%)偱偁傝丄偙傟傜偼憡屳攔懠揑偱偁偭偨丅梊屻夝愅偱偼NF1堎忢偼梊屻晄椙場巕丄NRAS曄堎偼梊屻椙岲場巕偱偁傝丄PTPN11曄堎徢椺偼嵞敪傗旕姲夝徢椺偑懡偄孹岦偵偁偭偨丅偙傟傑偱NF1偼堚揱巕偑戝偒偄偨傔曬崘偑彮側偔丄幚尡偱偼mTOR慾奞嵻偑桳岠惈偑偁傝丄暘巕昗揑栻偺奐敪偵傛傝梊屻偺夵慞傕婜懸偱偒傞偲巚傢傟偨丅傑偨NRAS曄堎偼CBFB-MYH11徢椺偵桳堄偵懡偔擣傔傜傟梊屻椙岲場巕偱偁偭偨偑丄偙偺尋媶偱摨偠RAS宱楬堎忢偱傕尨場堚揱巕偵傛傝梊屻偑堎側傞偙偲偑敾柧偟偨丅
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